Search Results - medical

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Zika DNA Vaccine
Technology Overview: A plasmid DNA vaccine thatencodes a secreted form of non-structural protein 1(secNS1). It is highly immunogenic and offers completesystemic protection from Zika in vaccinated mice. Thevaccine protects and completely eliminates ZIKA virus inpreclinical studies. We have modified the plasmid DNAvaccine to include a leader sequence...
Published: 8/26/2018   |   Inventor(s): Eric Gowans, Branka Grubor-Bauk, Danushka Wijesundara
Keywords(s):  
Category(s): Medical, Diagnostic, Biology, Therapeutic, Drug Discovery, Biotechnology
Reduction of Bone Loss
Market NeedOsteoporosis is a prevalent but grossly undertreated condition, with only 10% of individuals with osteoporosis in Australia being treated. In women, osteoporosis is a serious consequence of menopausal bone loss. Destructive bone erosion is also a serious complication of several primary and metastatic musculoskeletal cancers, and chronic ...
Published: 8/26/2018   |   Inventor(s): Gerald Atkins
Keywords(s):  
Category(s): Medical
Methods and Products for Preventing and/or Treating Microorganism Infections (Formerly Therapy for the treatment of bacterial biofilms)
A novel therapy for the treatment of bacterial biofilmsDescriptionChronic infections such as those exhibited in chronic wounds, pneumonia in cystic fibrosis patients, chronic otitis and chronic rhinosinusitis affect millions of people a year and many deaths can occur as a consequence. Whilst many targeted treatments of bacterial pathogenesis has fo...
Published: 8/26/2018   |   Inventor(s): Peter-John Wormald, Sarah Vreugde
Keywords(s):  
Category(s): Medical, Biotechnology, Biomedical, Therapeutic
Cellular Vaccine and Method of Inducing an Immune Response in a Subject (formerly referred to as Suicide Gene NSP4 as an Augment for DNA Vaccines)
Technology OverviewOur cytolytic DNA vaccines encode a viral immunogen and a cytolytic protein to induce necrosis in targeted cells resulting in release of a range of damage associated molecular patterns (DAMPs) and cross presentation of the immunogen. This results in increased virus-specific immune responses. The goal is to attract circulating d...
Published: 8/14/2018   |   Inventor(s): Eric Gowans
Keywords(s):  
Category(s): Medical, Drug Discovery
ELISA-On-A-Stick: in vivo detection and measurement of biological materials
Market NeedIn order to understand the role of the immune system in pain, it is essential to monitor the concentration of localized pro-inflammatory cytokines in the spinal cord.Cytokines are the small proteins secreted from cells. They are indicators of the functional status of the human immune system and the biomarkers for many diseases.Certain p...
Published: 5/30/2018   |   Inventor(s): Ewa Goldys, Guozhen Liu, Mark Hutchinson
Keywords(s):  
Category(s): Medical, Devices, Diagnostic, Drug Delivery, Nanotechnology, Optics, Biology, Biotechnology, Therapeutic
A novel diagnostic for human carcinomas as the first step towards treatment
Market Need:Unlike most mammals, humans cannot synthesise the sialic acid N glycolylneuraminic acid (NeuGc). Nevertheless, NeuGc is understood to be preferentially taken up by human cancerous cells and subsequently secreted into the blood. Hence, NeuGc represents a specific biomarker for detection of a range of human cancers.Currently available re...
Published: 5/30/2018   |   Inventor(s): James Paton, Michael Jennings
Keywords(s):  
Category(s): Medical, Biology, Diagnostic, Therapeutic
Reducing the risk of ovarian hyper-stimulation syndrome and improving oocyte maturation in IVF
Market Need:A significant proportion of children in western and developing countries are now born using assisted reproduction technologies, including through in vitro fertilization (IVF). The IVF process typically involves:- hormonally stimulating the ovaries of women to produce multiple growing follicles- collecting the ova from these ...
Published: 2/1/2018   |   Inventor(s): Mark Nottle
Keywords(s):  
Category(s): Medical, Biology
Treatment of atrial fibrillation associated with obesity using endothelin receptor antagonists
Atrial fibrosis prevention in obese and overweight patients Overweight patients are at increased risk of atrial fibrillation (AF) and atrial fibrosis. Treatment of this group with endothelin receptor antagonists (ERAs) could reduce that risk and obviate the need for more invasive and expensive treatments for atrial fibrillation, such as ablation pr...
Published: 1/28/2018   |   Inventor(s):  
Keywords(s): Biology, Biopharmaceuticals, Cardiovascular Disease, Drug Delivery, Drug Development
Category(s): Medical, Biology, Biomedical, Biotechnology, Therapeutic
Methods for diagnosis and treatment of Coronary Artery Spasm
Market NeedCardiovascular disease remains the most common killer in the world. Angina Pectoris, a leading symptom of cardiovascular disease, is estimated to affect over 10m people in the US, with over 500,000 new patients presenting each year. The pharmaceutical market for Angina Pectoris is valued at approximately $9bn, and growing at a CAGR of o...
Published: 1/21/2018   |   Inventor(s): John Horowitz
Keywords(s): Cardiovascular Disease
Category(s): Medical, Biomedical, Diagnostic, Therapeutic
A novel early detection biomarker for risk and severity of cardiac fibrosis
Market NeedCardiovascular disease (CVD) is the leading cause of death worldwide, accounting for the death of 17.1 million people. Currently patients are assessed for risk of heart disease by simple blood test for biomarkers such as cholesterol, troponin and brain natriuretic peptides. However, the predictive value of these biomarkers and hence the ...
Published: 11/20/2017   |   Inventor(s): Doan Ngo
Keywords(s): Biology, Cardiovascular Disease
Category(s): Medical, Biology, Biomedical, Diagnostic
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