Search Results - eric gowans

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Zika DNA Vaccine
Technology Overview: A plasmid DNA vaccine thatencodes a secreted form of non-structural protein 1(secNS1). It is highly immunogenic and offers completesystemic protection from Zika in vaccinated mice. Thevaccine protects and completely eliminates ZIKA virus inpreclinical studies. We have modified the plasmid DNAvaccine to include a leader sequence...
Published: 8/26/2018   |   Inventor(s): Branka Grubor-Bauk, Eric Gowans, Danushka Wijesundara
Category(s): Medical, Diagnostic, Biology, Therapeutic, Drug Discovery, Biotechnology
Cellular Vaccine and Method of Inducing an Immune Response in a Subject (formerly referred to as Suicide Gene NSP4 as an Augment for DNA Vaccines)
Technology OverviewOur cytolytic DNA vaccines encode a viral immunogen and a cytolytic protein to induce necrosis in targeted cells resulting in release of a range of damage associated molecular patterns (DAMPs) and cross presentation of the immunogen.  This results in increased virus-specific immune responses.  The goal is to attract circulating dendritic...
Published: 8/14/2018   |   Inventor(s): Eric Gowans
Category(s): Medical, Drug Discovery