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Treatment of atrial fibrillation associated with obesity using endothelin receptor antagonists
Atrial fibrosis prevention in obese and overweight patients Overweight patients are at increased risk of atrial fibrillation (AF) and atrial fibrosis. Treatment of this group with endothelin receptor antagonists (ERAs) could reduce that risk and obviate the need for more invasive and expensive treatments for atrial fibrillation, such as ablation pr...
Published: 1/28/2018   |   Inventor(s):  
Keywords(s): Biology, Biopharmaceuticals, Cardiovascular Disease, Drug Delivery, Drug Development
Category(s): Medical, Biology, Biomedical, Biotechnology, Therapeutic
Methods for diagnosis and treatment of Coronary Artery Spasm
Market NeedCardiovascular disease remains the most common killer in the world. Angina Pectoris, a leading symptom of cardiovascular disease, is estimated to affect over 10m people in the US, with over 500,000 new patients presenting each year. The pharmaceutical market for Angina Pectoris is valued at approximately $9bn, and growing at a CAGR of o...
Published: 1/21/2018   |   Inventor(s): John HOROWITZ
Keywords(s): Cardiovascular Disease
Category(s): Medical, Biomedical, Diagnostic, Therapeutic
A novel early detection biomarker for risk and severity of cardiac fibrosis
Market NeedCardiovascular disease (CVD) is the leading cause of death worldwide, accounting for the death of 17.1 million people. Currently patients are assessed for risk of heart disease by simple blood test for biomarkers such as cholesterol, troponin and brain natriuretic peptides. However, the predictive value of these biomarkers and hence the ...
Published: 11/20/2017   |   Inventor(s): Doan Ngo
Keywords(s): Biology, Cardiovascular Disease
Category(s): Medical, Biology, Biomedical, Diagnostic
A novel therapy for the treatment of bacterial biofilms
Market NeedChronic infections such as those exhibited in chronic wounds, chronic and relapsing respiratory infections, chronic osteomyelitis (orthopaedic implant-associated infections) and chronic rhinosinusitis affect millions of people worldwide and play an important role in morbidity and mortality, particularly among the elderly. The repetitive ...
Published: 10/12/2017   |   Inventor(s): Peter-John Wormald, Sarah Vreugde
Category(s): Medical, Biomedical, Biotechnology, Therapeutic
Annexin A2 as a novel diagnostic marker for serous ovarian cancer
Technology Background: We have recently shown that annexin A2 is highly expressed in 90% of serous ovarian cancers, which is the most common subtype and is actively involved in the process of ovarian cancer metastasis. Moreover, we have also shown that local upregulation of annexin A2 within the tumour is reflected in a systemic ~2.0-fold increase...
Published: 6/24/2015   |   Inventor(s): Carmela Ricciardelli, Martin OEHLER
Keywords(s): Biopharmaceuticals, Cancer, Diagnostics, Oncology, Reproductive
Category(s): Biomedical, Biotechnology, Diagnostic, Proteomics
Clinical Trial Capability
Researchers who perform both clinical work and research in their specific fields of expertise are highly sort after by industry to study the latest therapies. They provide customers with credible, reliable and unbiased results which are highly regarded by regulators.The University of Adelaide's areas of expertise include:- Pain and Anaesthesia- Car...
Published: 10/27/2013   |   Inventor(s):  
Keywords(s): Addiction / Drug Dependency, Analytical Services, Anti-infectives, Assays, AutoImmune, Biology, Biomaterials, Biopharmaceuticals, Biosensing, Cancer, Cardiovascular Disease, CNS, Contraception, Diabetes, Drug Delivery, Drug Development, Endocrinology, Gastroenterology, Gastrointestinal, Gene/Cell Therapy, Genetic Disorders, Haematology, Hormone Therapy, Immunology, Infectious Disease, Inflammation, Medical Device, Mental Health, Metabolic Disease, Musculoskelatal, Neurology, Oncology, Ophthalmic, Osteo / Bone, Pathology, Pharmacogenetics, Pulmonary, Regenerative Medicine, Renal, Reproductive, Respiritory, Skin/Dermatological, Systems Biology, Urological, Vaccines
Category(s): Medical, Biomedical, Biotechnology, Dental, Devices, Diagnostic, Drug Delivery, Drug Discovery, Drug Screening, Gene Therapy, Genomics/Genetics, Nanotechnology, Therapeutic
Gastric Cancer Detection Test
Gastric cancer (GC) is the fourth most common cancer in the world and the second leading cause of cancer-related death. In Australia, the age standardised incident rate (ASR) is 9-10 per 100,000 people and over 11,000 deaths were recorded between 1996 and 2006. The current diagnostic strategy for GC is inadequate. The ability to detect early stage...
Published: 10/28/2012   |   Inventor(s):  
Keywords(s): Cancer, Diagnostics, Gastroenterology, Oncology
Category(s): Biotechnology, Proteomics, Medical, Diagnostic, Biomedical
Chemokine Receptor Inhibition and Anti-Tumour Immunity
Description of the Technology CCX-CKR expressed in malignant melanoma and many other metastatic cancers. Circumstantial evidence from the literature predicted that interfering with the expression and/or function of CCX-CKR would exacerbate melanoma growth and metastasis. To test this hypothesis, a series of experiments in the B16 murine melan...
Published: 10/28/2012   |   Inventor(s):  
Keywords(s): Cancer, Drug Development, Oncology, Vaccines
Category(s): Therapeutic, Medical, Biomedical, Biotechnology
Neuroimmunology Laboratory
The University of Adelaide is able to deliver in vivo preclinical testing services in the field of behavioural neuroscience. Behavioural tests for mice available in our Neuroimmunology laboratory include tests for: * depression-like behaviour (e.g. Swim Test) * cognition-like behaviour (e.g. Barnes Maze, or Novel Object R...
Published: 8/27/2012   |   Inventor(s): Bernhard Baune
Keywords(s): Analytical Services, Consulting, Immunology, Mental Health
Category(s): Medical, Biomedical
Optical Fibre Dip Sensor
The Institute for Photonics & Advanced Sensing (IPAS) brings together physicists, chemists and biologists to pursue a new transdisciplinary approach to science. Researchers are developing novel photonic, sensing and measurement technologies that will change the way science is done within traditional discipline areas, stimulating the creation of...
Published: 2/22/2012   |   Inventor(s): Tanya Monro
Keywords(s): Biosensing, Diagnostics, Informatics, Instrumentation, Mechanical Engineering, Medical Device, Sensing
Category(s): Medical, Engineering, Devices, Bioinformatics, Biomedical, Diagnostic, Electrical, Materials, Optics