Search Results - Biology

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Zika DNA Vaccine
Technology Overview: A plasmid DNA vaccine thatencodes a secreted form of non-structural protein 1(secNS1). It is highly immunogenic and offers completesystemic protection from Zika in vaccinated mice. Thevaccine protects and completely eliminates ZIKA virus inpreclinical studies. We have modified the plasmid DNAvaccine to include a leader sequence...
Published: 8/26/2018   |   Inventor(s): Eric Gowans, Branka Grubor-Bauk, Danushka Wijesundara
Keywords(s):  
Category(s): Medical, Diagnostic, Biology, Therapeutic, Drug Discovery, Biotechnology
ELISA-On-A-Stick: in vivo detection and measurement of biological materials
Market NeedIn order to understand the role of the molecular signalling events of the immune system it is essential to monitor the concentration of localized pro-inflammatory cytokines in key anatomical compartments repeatedly over time.Cytokines are the small proteins secreted from cells. They are indicators of the functional status of the human i...
Published: 5/30/2018   |   Inventor(s): Ewa Goldys, Guozhen Liu, Mark Hutchinson
Keywords(s):  
Category(s): Medical, Devices, Diagnostic, Drug Delivery, Nanotechnology, Optics, Biology, Biotechnology, Therapeutic
A novel diagnostic for human carcinomas as the first step towards treatment
Market Need:Unlike most mammals, humans cannot synthesise the sialic acid N glycolylneuraminic acid (NeuGc). Nevertheless, NeuGc is understood to be preferentially taken up by human cancerous cells and subsequently secreted into the blood. Hence, NeuGc represents a specific biomarker for detection of a range of human cancers.Currently available re...
Published: 5/30/2018   |   Inventor(s): James Paton, Michael Jennings
Keywords(s):  
Category(s): Medical, Biology, Diagnostic, Therapeutic
Improving gamete quality to increase IVF outcomes
Market NeedInfertility affects one in five couples; with 40% of cases directly attributable to male factors, 40% attributable to female factors and the remainder due to fertility problems in both partners, or unknown causes.Most fertility treatments and technologies currently in clinical use focus on treating women, or treating their oocytes or emb...
Published: 5/30/2018   |   Inventor(s): Rebecca Robker, Macarena Bermudez-Gonzalez
Keywords(s):  
Category(s): Biology, Therapeutic
Non invasive embryo screening for improved human IVF outcomes
Market NeedDespite growth in industry demand, IVF cycles currently result in low success rates, with reports indicating less than 20% of cycles result in a live birth. While part of this is attributable to the physical environment of the individual patients, part of the high fail rate of IVF is attributable to the clinical elements of the IVF proc...
Published: 5/29/2018   |   Inventor(s): Jeremy Thompson, Hannah Brown, Martin Gosnell, John Ryan
Keywords(s):  
Category(s): Bioinformatics, Biology, Computer Software, Diagnostic, Imaging
Reducing the risk of ovarian hyper-stimulation syndrome and improving oocyte maturation in IVF
Market Need:A significant proportion of children in western and developing countries are now born using assisted reproduction technologies, including through in vitro fertilization (IVF). The IVF process typically involves:- hormonally stimulating the ovaries of women to produce multiple growing follicles- collecting the ova from these ...
Published: 2/1/2018   |   Inventor(s): Mark Nottle
Keywords(s):  
Category(s): Medical, Biology
Treatment of atrial fibrillation associated with obesity using endothelin receptor antagonists
Atrial fibrosis prevention in obese and overweight patients Overweight patients are at increased risk of atrial fibrillation (AF) and atrial fibrosis. Treatment of this group with endothelin receptor antagonists (ERAs) could reduce that risk and obviate the need for more invasive and expensive treatments for atrial fibrillation, such as ablation pr...
Published: 1/28/2018   |   Inventor(s):  
Keywords(s): Biology, Biopharmaceuticals, Cardiovascular Disease, Drug Delivery, Drug Development
Category(s): Medical, Biology, Biomedical, Biotechnology, Therapeutic
A novel early detection biomarker for risk and severity of cardiac fibrosis
Market NeedCardiovascular disease (CVD) is the leading cause of death worldwide, accounting for the death of 17.1 million people. Currently patients are assessed for risk of heart disease by simple blood test for biomarkers such as cholesterol, troponin and brain natriuretic peptides. However, the predictive value of these biomarkers and hence the ...
Published: 11/20/2017   |   Inventor(s): Doan Ngo
Keywords(s): Biology, Cardiovascular Disease
Category(s): Medical, Biology, Biomedical, Diagnostic
Biomarkers for prognosis, prevention and treatment of liver metastasis
Biomarkers for prognosis, prevention, and treatment of liver metastasisMarket Need Colorectal cancer (CRC) is a major cause of morbidity and mortality throughout the world and is the second most common cancer in both men and women in Australia. The risk of being diagnosed by age 85 is 1 in 10 for men, and 1 in 15 for women. The majority of CRC rela...
Published: 11/6/2017   |   Inventor(s): Ehud Hauben, Guy Maddern, Jennifer Hardingham, Peter Hewett
Keywords(s):  
Category(s): Diagnostic, Therapeutic, Biology
Commercialisation of algorithms that predict risk for pregnancy complications
Non-Invasive Diagnostic Test for Prediction of Pregnancy Complications Overview: Researchers at the University of Adelaide have identified a suite of genetic markers associated with increased risk of pregnancy complications. On average 25% of first time pregnancies in Australia are affected by one or more of four major complications: preeclampsia, ...
Published: 6/24/2015   |   Inventor(s): Claire Roberts, Gustaaf Dekker, Shalem Yiner-Lee Leemaqz
Keywords(s): Diagnostics, Reproductive
Category(s): Medical, Biology, Diagnostic, Genomics/Genetics